Francisco José Romero Campero

Group: Systems biology and biotechnology in microalgae

Position: US Tenured Professor

Contact:

Office: DS102

Phone: ext. 446008

Lab: LS104

Email:

Formation

Education and Research positions:
Bachelor Laureate in Mathematics (2003)
Ph.D. in Computer Science and Artificial Intelligence from the University of Seville (2008)

Research projects:
Evolution of Diurnal and Seasonal Rhythmic Networks in Chlorophyta, Charophyta and Bryophyta (ELECTRA). Proyecto Generación del Conocimiento
(123984OBI00). 96800€ January 2023-December 2025. PI
Study of the efficacy of innovative biostimulants derived from microalgae to tackle the adverse effects of climate change on tomato and wheat (MICROCLIMATT) GRUPOS
OPERATIVOS (AEI-AGRI), PROGRAMA NACIONAL DE DESARROLLO RURAL 96.497,71€. From March 2021 to February 2023. Co-PI
Integration of Multi-omic data to reveal the control of the Biosynthesis of Compounds of Biotechnological Interest in Ostreococcus tauri (MINOTAUR) Programa Estatal de I+D+i
Orientada a los Retos de la Sociedad 80.000 €. From January, 2018 to September, 2021. PI

Research Interests

My research integrates mathematical and computational techniques for multiomics data analysis and gene network construction and analysis to address molecular biology challenges in photosynthetic organisms from microalgae to crops. My scientific career comprises three stages: a PhD in Computer Science and Artificial Intelligence (2008), postdoctoral research in the UK and Spain focusing on multiomics data integration, and as independent PI since 2017. Currently, my research projects focus on characterizing the response and acclimation to light and temperature in photosynthetic organisms specifically using as model organisms Ostreococcus taui, Klebsormidium nitens, Mesotaenium endlicherianum and Marchantia polymorpha. I have published in Plant Cell, Nature Communications, and Genome Biology. At the University of Seville, I teach systems biology and omics technologies and have been the coordinator of the Master’s in Omics Data Analysis and Systems Biology.

Publications

Multiomics integration unveils photoperiodic plasticity in the molecular rhythms of marine phytoplankton.
Romero-Losada AB, Arvanitidou C, García-Gómez ME, Morales-Pineda M, Castro-Pérez MJ, Chew YP, van Ooijen G, García-González M, Romero-Campero FJ. Plant Cell. 2025 Feb 13;37(2):koaf033. doi: 10.1093/plcell/koaf033.
CONSTANS alters the circadian clock in Arabidopsis thaliana.
de Los Reyes P, Serrano-Bueno G, Romero-Campero FJ, Gao H, Romero JM, Valverde F. Mol Plant. 2024 Aug 5;17(8):1204-1220. doi: 10.1016/j.molp.2024.06.006. Epub 2024 Jun 17.
Transcriptomic characterization of the response to a microalgae extract in Arabidopsis thaliana and Solanum lycopersicum.
Arvanitidou C, Ramos-González M, Romero-Losada AB, García-Gómez ME, García-González M, Romero-Campero FJ. J Sci Food Agric. 2024 Aug 15;104(10):5789-5798. doi: 10.1002/jsfa.13422. Epub 2024 Mar 10.
Transcriptomic and Metabolomic Response to High Light in the Charophyte Alga Klebsormidium nitens.
Serrano-Pérez E, Romero-Losada AB, Morales-Pineda M, García-Gómez ME, Couso I, García-González M, Romero-Campero FJ. Front Plant Sci. 2022 May 6;13:855243. doi: 10.3389/fpls.2022.855243. eCollection 2022.
H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots.
Yin X, Romero-Campero FJ, de Los Reyes P, Yan P, Yang J, Tian G, Yang X, Mo X, Zhao S, Calonje M, Zhou Y. Nat Commun. 2021 Jan 12;12(1):315. doi: 10.1038/s41467-020-20614-1.

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