Julia Jiménez López

Group: Redox signaling in plants

Position: Postdoctoral researcher

Contact:

Laboratory: L103

Email:

Formation

Master’s Degree in Biotechnology, Universidad Pablo de Olavide, 2009-2013

MsC in Regenerative biomedicine, Universidad de Granada, 2013-2014

PhD in Biomedicine, Universidad de Granada, 2014-2019

National Youth Guarantee, Instituto de Bioquímica Vegetal y Fotosíntesis, Universidad de Sevilla, 2019-2020.

Postdoctoral Fellowship, Instituto de Bioquímica Vegetal y Fotosíntesis, CSIC, 2022-2025.

Research Interests

My research career has been focused in the field of biochemistry and molecular biology. During my predoctoral stage, my studies were focused on the development of nanoformulations for the improvement of antitumor drugs against lung cancer. Currently, my scientific interest has been redirected to plant biotechnology, specifically, to the study of chloroplast redox regulation systems in Arabidopsis thaliana, with the aim of understanding the adaptive mechanisms of plants to different environmental conditions. This knowledge would allow the design of biotechnological strategies that would improve plant tolerance to different environmental stresses.

Publications

Hernández ML, Jiménez-López J, Cejudo FJ, Pérez-Ruiz JM. 2-Cys peroxiredoxins contribute to thylakoid lipid unsaturation by affecting ω-3 fatty acid desaturase 8. Plant Physiol. 2024 May 31;195(2):1521-1535. doi: 10.1093/plphys/kiae102
Gallardo-Martínez AM, Jiménez-López J, Hernández ML, Pérez-Ruiz JM, Cejudo FJ. Plastid 2-Cys peroxiredoxins are essential for embryogenesis in Arabidopsis. Redox Biol. 2023 Jun;62:102645. doi: 10.1016/j.redox.2023.102645. Epub 2023 Mar 1. PMID: 36898225; PMCID: PMC10020101.
Ojeda V, Jiménez-López J, Romero-Campero FJ, Cejudo FJ, Pérez-Ruiz JM. A chloroplast redox relay adapts plastid metabolism to light and affects cytosolic protein quality control. Plant Physiol. 2021 Sep 4;187(1):88-102. doi: 10.1093/plphys/kiab246. PMID: 34618130; PMCID: PMC8418392.
Jiménez-López J, Bravo-Caparrós I, Cabeza L, Nieto FR, Ortiz R, Perazzoli G, Fernández-Segura E, Cañizares FJ, Baeyens JM, Melguizo C, Prados J. Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes. Biomed Pharmacother. 2021 Jan;133:111059. doi: 10.1016/j.biopha.2020.111059. Epub 2020 Dec 9. PMID: 33378963.
Jiménez-López J, El-Hammadi MM, Ortiz R, Cayero-Otero MD, Cabeza L, Perazzoli G, Martin-Banderas L, Baeyens JM, Prados J, Melguizo C. A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer. Pharmacol Res. 2019 Mar;141:451-465. doi: 10.1016/j.phrs.2019.01.013. Epub 2019 Jan 8. PMID: 30634051.
 
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