Sandra Díaz Troya

Group: Gene expression and metabolic regulation in cyanobacteria

Position: Associate Professor

Contact:

Office: tel. 954139180 ext. 446068
E-mail:

Formation

Degree in Biological Sciences. University of Seville. 2000
PhD in Biology. University of Seville. 2009

Research Interests

My research investigates glycogen metabolism in cyanobacteria, primarily using the model organism Synechocystis sp. PCC 6803, and its impact on adaptation to diverse environmental conditions, with special emphasis on the crucial role of glycogen as a metabolic buffer. I am particularly focused on its interactions with central metabolism and the cellular redox state. A comprehensive understanding of these processes is essential for the efficient design of genetically modified organisms for the production of compounds of interest.

Publications

Ortega-Martínez P, Nikkanen L, Wey LT, Florencio FJ, Allahverdiyeva Y, Díaz-Troya S. Glycogen synthesis prevents metabolic imbalance and disruption of photosynthetic electron transport from photosystem II during transition to photomixotrophy in Synechocystis sp. PCC 6803. New Phytol. 2024 Jul;243(1):162-179. doi: 10.1111/nph.19793. Epub 2024 May 6. PMID: 38706429.
Ortega-Martínez P, Roldán M, Díaz-Troya S, Florencio FJ. Stress response requires an efficient connection between glycogen and central carbon metabolism by phosphoglucomutases in cyanobacteria. J Exp Bot. 2023 Mar 13;74(5):1532-1550. doi: 10.1093/jxb/erac474. PMID: 36454663; PMCID: PMC10010611.
Díaz-Troya S, Roldán M, Mallén-Ponce MJ, Ortega-Martínez P, Florencio FJ. Lethality caused by ADP-glucose accumulation is suppressed by salt-induced carbon flux redirection in cyanobacteria. J Exp Bot. 2020 Mar 25;71(6):2005-2017. doi: 10.1093/jxb/erz559. PMID: 31858138; PMCID: PMC7242066.
Kadouche D, Ducatez M, Cenci U, Tirtiaux C, Suzuki E, Nakamura Y, Putaux JL, Terrasson AD, Diaz-Troya S, Florencio FJ, Arias MC, Striebeck A, Palcic M, Ball SG, Colleoni C. Characterization of Function of the GlgA2 Glycogen/Starch Synthase in Cyanobacterium sp. Clg1 Highlights Convergent Evolution of Glycogen Metabolism into Starch Granule Aggregation. Plant Physiol. 2016 Jul;171(3):1879-92. doi: 10.1104/pp.16.00049. Epub 2016 May 19. PMID: 27208262; PMCID: PMC4936547.
Díaz-Troya S, López-Maury L, Sánchez-Riego AM, Roldán M, Florencio FJ. Redox regulation of glycogen biosynthesis in the cyanobacterium Synechocystis sp. PCC 6803: analysis of the AGP and glycogen synthases. Mol Plant. 2014 Jan;7(1):87-100. doi: 10.1093/mp/sst137. Epub 2013 Oct 11. PMID: 24121290.
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