Cristina Sarasa Buisán
Group: Biology and Genetic Engineering of Multicellular Cyanobacteria
Position: Postdoctoal researcher
Contact:
Phone. 954489500 ext. 446092
Email:
Formation
Graduate in Biological Science, University of Salamanca, 2014
PhD in Biochemistry and Molecular Biology, University of Zaragoza, 2022
Research Interests
Currently, as a Postdoctoral researcher at the IBVF, my work centers on developing genetic tools for genome editing of cyanobacteria from complex ecological communities using the CRISPR-associated transposition (CAST) system. Our primary target is the cyanobiont Nostoc azollae, an obligate symbiont of aquatic Azolla ferns. N. azollae has an eroded genome and cannot be cultivated isolated under laboratory conditions. To facilitate genetic editing of this cyanobiont, our project aims to develop an efficient in planta transformation system and robust RNA-guided transposition tools. This project is funded by the Symbiosis in Aquatic Systems Initiative by the Gordon and Betty Moore Foundation, which brings together the work of various research centers. The principal investigators include Enrique Flores my direct supervisor at IBVF-CSIC, Peter Lindblad from Uppsala University, Henriette Schlupmann from Utrecht University, and Sandra Nierzwicki-Bauer from Rensselaer Polytechnic Institute in Troy, NY.
My previous PhD research at the University of Zaragoza, which part was done in collaboration with researchers from the IBVF, focused on the functional and biochemical characterization of the transcriptional regulations of the FUR (Ferric Uptake Regulator) family in Anabaena sp. PCC 7120, with a particular emphasis on the PerR and Zur regulators.
Publications